November 30, 2025
Gaming

binding of isaac samson

Samson is one of the more unique and engaging characters in The Binding of Isaac, known for his rage-fueled abilities and aggressive playstyle. Unlocked by skipping two treasure rooms in a run and then defeating Mom, Samson offers a fresh experience for players who enjoy building power through taking damage. His mechanics reward risky gameplay and strategic positioning, making him a fan favorite for those who like pushing their luck. Whether you’re just starting out or aiming for advanced challenges, learning how to play Samson effectively can greatly increase your chances of success in The Binding of Isaac: Rebirth and its expansions.

How to Unlock Samson

In The Binding of Isaac: Rebirth, Samson is unlocked by completing two floors in a row without picking up any items from Treasure Rooms and then defeating Mom. This challenge teaches discipline and restraint, especially for players used to maximizing item pickups early on. In later versions or after certain updates, Samson may be unlocked by default depending on the platform or expansion.

Tips for Unlocking

  • Pick up consumables and shop items, but avoid the golden treasure rooms.
  • Use familiars, bombs, and environmental advantages to make up for lack of power.
  • Play as Azazel or another strong starting character to improve your odds.

Samson’s Starting Stats and Abilities

Samson begins each run with unique stats and one powerful passive ability that defines his playstyle: Bloody Lust.

Starting Loadout

  • Health: 1 red heart, 1 black heart
  • Speed: 1.00 (average)
  • Damage: 3.5 (base)
  • Range: 6.5
  • Starting Item: Bloody Lust

Bloody Lust Explained

Bloody Lust increases Samson’s damage each time he takes damage during a floor. The boost stacks with each hit, allowing for a potential high-damage output by the time a boss fight begins. The bonus resets at the start of each new floor, which encourages aggressive play and taking calculated risks.

Strengths of Playing as Samson

Samson’s gameplay is based around the idea of growing stronger through pain. Players who understand how to manage damage and use health resources wisely will find him incredibly rewarding to play.

Key Strengths

  • Scalable Damage: Each hit you take increases your power, turning bad rooms into power-ups.
  • Strong with Devil Deals: His black heart gives early potential for powerful trades.
  • Synergy Potential: Items that provide invincibility or controlled damage (like IV Bag or Blood Rights) become significantly more useful.

Weaknesses and Challenges

Despite his strengths, Samson can be a risky character for beginners or those with a more defensive mindset. Managing health and deciding when to take damage requires experience and confidence.

Notable Weaknesses

  • Health Management: Losing too much health early can snowball into an early death.
  • Floor Reset: Bloody Lust resets each floor, so early fights on new floors are always underpowered.
  • Devil Deal Risk: Trading away red hearts leaves less room for error.

Best Items for Samson

Samson has incredible synergy with items that let him take damage safely or enhance the effects of Bloody Lust. These items can turn him into a powerhouse.

Top Synergistic Items

  • IV Bag: Allows you to damage yourself on command and boost Bloody Lust before boss fights.
  • Bloody Penny: Works well with blood donation machines for health recovery loops.
  • Guppy’s Paw: Can trade red hearts for soul hearts, making Devil Deals safer.
  • Book of Shadows: Grants invincibility, perfect for strategic damage or blood machines.
  • Blood Rights: Damages Samson for full-room damage, synergizing perfectly with his passive.
  • Spirit of the Night / The Pact / The Mark: High-risk Devil Deal items that offer big damage boosts and soul hearts.

Strategies for Playing Samson

Playing Samson well is about knowing when to take damage and when to play safe. His skill ceiling is high, but with practice, you can make him one of the strongest characters in your Isaac roster.

Early Floor Strategy

  • Play cautiously in the early rooms to avoid losing unnecessary health.
  • Use your black heart carefully let it clear rooms if possible.
  • Find tinted rocks or secret rooms early for extra soul hearts.

Mid-Game Strategy

  • Look for shops with health items or donation machines to capitalize on Bloody Lust.
  • Take Devil Deals that give damage or soul hearts but avoid going down to just one heart unless confident.
  • Use self-damage strategically to power up before boss rooms.

Late-Game Strategy

  • Focus on sustaining health using soul hearts or regeneration items.
  • Consider angel deals if low on red hearts and want to avoid further risk.
  • Use spacebar items like The Nail or Book of Revelations to gain health while still building damage.

Alternate Versions: Tainted Samson

In The Binding of Isaac: Repentance, players can unlock alternate ‘tainted’ versions of each character. Tainted Samson is a radical rework of the original, offering a more aggressive but time-limited combat style.

Tainted Samson Overview

  • Uses a berserk mode that temporarily replaces normal tears with melee swings.
  • Activates berserk by collecting blood charges from enemies and items.
  • Emphasizes fast-paced, close-range combat with high risk and high reward.

Tainted Samson is especially strong when paired with speed and invincibility items, allowing him to maintain berserk mode longer and cut through enemies in waves. However, his lack of range makes certain bosses and projectile-heavy rooms more difficult.

Achievements and Unlocks

Using Samson in your runs will eventually unlock powerful items that benefit future characters.

Notable Unlocks

  • Bloody Lust: Becomes available for all characters after a successful run.
  • Samson’s Chains: A passive item that deals damage and breaks rocks while moving.
  • Lusty Blood: Provides temporary damage boosts after killing enemies in a room very synergistic with crowd control.

Samson is a dynamic character in The Binding of Isaac, ideal for players who enjoy high-risk, high-reward gameplay. His passive ability, Bloody Lust, allows for incredible scaling when used correctly, and his synergy with damage-based items and health manipulation makes him a fun and deadly choice. With careful health management, strategic damage intake, and a bit of luck, Samson can clear the hardest challenges the game has to offer. Whether you prefer the classic version or the berserk fury of Tainted Samson, mastering his mechanics is both satisfying and effective for progressing deeper into Isaac’s twisted world.